What is VG?

Vegetable Glycerin Studies

Glycerol is one of the most benign organic liquids known to man. It is hype-allergenic, non-carcinigeic, non teratogenic and non-mutagenic. It is metabolized quite easily by a process called beta-oxidation. This process results in the production of CO2 and H2O and is a quite normal, common, and natural catabolic process.

The following is a few excerpts from a study called SIDS initial assessment profile of Glycerol Citation

  • Glycerol is of low toxicity when ingested, inhaled, or in contact with skin
  • The NOACE for local irritant effects to the upper respiratory tract is 165 mg/m3
  • Glycerol is of a low order of acute oral and dermal toxicity with LD50 values in excess of 4000 mg/kw bw.
  • Glycerol has low potential to irritate the skin and the eye
  • Glycerol is not a skin irritant
  • Glycerol does not induce gene mutations in bacterial strains, chromosomal effects in mammalian cells or primary DNA damage in vitro
  • Overall, glycerol is not considered to possess genotoxic potential
  • No effects on fertility and reproductive performance were observed
  • No further work is indicated by this study, because of the low hazard potential of this substance.

       Vegetable glycerin is approved by the FDA for use in various forms. Products with Vegetable Glycerin can be found in various common items around your house. A few examples include:

Sugar substitute
In Beauty products including makeup, mousse, shampoo, bubble bath, after shave, and deodorant
Pet food
Skin and hand cream
Baked goods - increase moisture
As a thick gel for creams, gel capsule pills, rubs and jellies
Eye & ear drops, toothpastes, pastes, and many dental care products 

          Glycerine is classified by the U.S. Food and Drug Administration (FDA) as "generally recognized as safe" (GRAS) and complies with specifications for the Food Chemicals Codex (FCC), United States Pharmacopeia (USP), and European Pharmacopoeia (Ph. Eur. or EP) E244. It is manufactured according to current Good Manufacturing Practices (cGMP) and is shipped according to applicable Good Trade and Distribution Practices (GTDP). Citation
Vegetable Glycerin studies